Residual effects of tracer in sequential double label deoxyglucose studies

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Residual effects of tracer in sequential double label deoxyglucose studies.

The validity of sequential double label deoxyglucose (DG) determinations of local metabolic rate for glucose (IMRglc) was examined by quantifying the degree of trapping of residual first DG tracer during the second experimental period. One sciatic nerve was repetitively stimulated for 25 min, beginning either at the time of the DG injection or 25 min later. IMRglc in the ipsilateral dorsal horn...

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A sequential double-label 2-deoxyglucose method for measuring regional cerebral metabolism.

A radiographic technique involving the use of 2-deoxyglucose (DG) has recently been introduced for the study of regional cerebral metabolism v. Its usefulness is based on the metabolic properties of DG, which bear both striking resemblances and differences to that of the natural substrate, o-glucose. Like D-glucose, DG is transported from the blood into brain cells and is phosphorylated by hexo...

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The functional organization of visual cortical area 17/18 of the ferret was studied using a double-label 2-deoxyglucose (2-DG) method. Animals were stimulated sequentially with moving gratings of 2 different orientations. Elongated orientational patches running roughly at a right angle into the area 17/18 border were seen. The orientation maps were similar in areas 17 and 18. When animals were ...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 1992

ISSN: 0304-3940

DOI: 10.1016/0304-3940(92)90777-5